Ingredients

What's actually in the jar

Tap an ingredient to see what it does, the dose behind it — and which chews it works in.

Omega-3 Fish Oil

Omega-3 Fish Oil

Skin & Coat

300 mg EPA + DHA per serving. These fatty acids get built straight into skin and immune cell membranes, where they help maintain a healthy inflammatory response — a more resilient skin barrier through seasonal ups and downs, and a softer, glossier coat. Sourced from wild-caught fish and tested for purity, every batch.

Quercetin

Quercetin

Itch Relief

100 mg per serving. Nature's antihistamine, found in apples, red onions and berries. This plant flavonoid interacts with mast cells — the immune cells that release histamine when your dog meets pollen, dust or grass — helping keep them calm and steady through the season.

Colostrum

Colostrum

Immune

200 mg per serving. First-milk goodness rich in immunoglobulins, lactoferrin and growth factors. It helps maintain the gut lining and supports balanced immune signalling — and since gut and skin are in constant conversation, a calm gut is a lot for an itchy dog.

Astragalus Root

Astragalus Root

Immune Balance

100 mg extract per serving. An adaptogen for the immune system: rather than switching immunity up or down, its polysaccharides and saponins help promote balance between the two arms that tip out of proportion in sensitive dogs — while supporting the body's own antioxidant defences.

Turmeric Root

Turmeric Root

Soothing

100 mg extract per serving. Curcumin works upstream, helping modulate NF-κB — the body's master switch for inflammation. That supports comfortable skin and joints for dogs whose itching turns into hot patches and restless nights. A concentrated extract, not kitchen-spice levels.

Bromelain

Bromelain

Enzymes

50 mg per serving. Pineapple-stem enzymes with two jobs: the classic absorption partner for curcumin and quercetin, and a helper for a balanced inflammatory response and comfortable digestion in its own right.

Black Pepper Extract

Black Pepper Extract

Absorption

5 mg per serving, standardised to 95% piperine. The doorman of the formula: piperine slows the rapid breakdown of plant compounds in the gut wall and liver, so more of what your dog swallows actually reaches the bloodstream instead of passing straight through.

Zinc (Chelated)

Zinc (Chelated)

Skin Barrier

15 mg per serving. The cofactor behind the enzymes that build keratin and knit the skin barrier together. We use an amino-acid-bound (chelated) form, because that bond helps protect zinc on its way through the gut and supports better uptake.

Probiotics

Probiotics

Gut Health

2 billion CFU of multi-strain good bacteria per serving. Around 70% of immune tissue sits along the gut, where bacteria help train immune cells to tell friend from foe. A diverse microbiome supports measured responses to everyday triggers — because healthy skin starts on the inside.

Vitamin E

Vitamin E

Skin Barrier

An antioxidant that backs up the skin barrier, protects cells from oxidative stress and adds that brag-worthy shine to the coat.

Natural Salmon Flavor

Natural Salmon Flavor

Taste

The reason your dog thinks this is a treat and not the healthy stuff. Real, natural flavor — nothing artificial, and no chicken or beef anywhere in the recipe.

Our philosophy

Why these ingredients?

Thousands of supplement ingredients sound impressive on a label. We hold every candidate to three simple rules — and most don't make the cut.

1.

Proven first

Every active has published research behind it and a clear job to do in the chew. Trendy extras with thin evidence stay out.

2.

Dosed like it matters

An ingredient only works at the right amount. We formulate with vets to hit meaningful doses — not label-decoration sprinkles.

3.

Nothing extra

No fillers, no artificial colors or flavors. If it isn't doing a job for your dog, it isn't in the jar.

Every claim, linked to the study behind it

Nine actives from our Allergy & Itch chew, each chosen for a reason — and every claim links to the published study behind it. Tap an ingredient and open The Research to read them all.

Omega-3 Fatty Acids

300 mg EPA + DHA

EPA and DHA get built straight into skin and immune cell membranes, where they help maintain a healthy inflammatory response. The result: a more resilient skin barrier through seasonal ups and downs, and a softer, glossier coat.

  • Itchy, allergy-prone dogs showed improved skin scores after 10 weeks of daily omega-3s; placebo dogs did not (Mueller 2004).Canine RCT
  • Dogs with dull coats showed visible improvement from day 60, with omega-3s measurably built into hair shafts and skin lipids (Combarros 2020).Canine RCT
  • Atopic dogs on oral omega-3s stayed comfortable on a lower daily medication dose than dogs on placebo oil (Schäfer 2024).Canine RCT

Colostrum

200 mg

The first milk after calving, rich in immunoglobulins, lactoferrin and growth factors. It helps maintain the gut lining and supports balanced immune signalling — and since gut and skin are in constant conversation, a calm gut is a lot for an itchy dog.

  • Dogs fed bovine colostrum showed a stronger vaccine response, higher faecal IgA and greater gut microbiota stability (Satyaraj 2013).Canine trial
  • 20 days of colostrum supported a healthier intestinal lining, with permeability markers moving back toward normal versus placebo (Hałasa 2017).Human RCT
  • Oral colostrum vesicles supported calmer skin and lower serum IgE while reshaping gut bacteria — the gut–skin axis at work (Mun 2025).Preclinical

Astragalus Root

100 mg extract

An adaptogen for the immune system. Rather than switching immunity up or down, its polysaccharides and saponins help promote balance between the two arms that tip out of proportion in sensitive dogs — while supporting the body's own antioxidant defences.

  • Beagles given Astragalus polysaccharide showed improved immune and antioxidant status and lower inflammatory markers (Luo 2023).Canine trial
  • Oral Astragalus supported healthier skin in an allergic dermatitis model, with milder lesions than untreated controls (Lee 2007).Preclinical
  • Astragalus supported a more balanced Th1/Th2 profile with fewer eosinophils in an allergen-driven model (Chen 2014).Preclinical

Quercetin

100 mg

Nicknamed "nature's antihistamine." This plant flavonoid interacts with mast cells — the immune cells that release histamine when your dog meets pollen, dust or grass — helping keep them calm and steady through the season.

  • In 30 dogs, a 28-day quercetin supplement lowered faecal calprotectin, cortisol and N-methylhistamine, a histamine breakdown marker (Atuahene 2023).Canine trial
  • In cultured mast cells, quercetin held back histamine release and outperformed cromolyn as a mast cell stabiliser (Weng 2012).In vitro
  • A meta-analysis of 13 allergy studies linked quercetin to lower IgE and histamine and a rebalanced Th1/Th2 profile (Li 2025).Meta-analysis

Turmeric Root

100 mg extract

Curcumin works upstream, helping modulate NF-κB — the body's master switch for inflammation. That supports comfortable skin and joints for dogs whose itching turns into hot patches and restless nights. A concentrated extract, not kitchen-spice levels.

  • In retired police dogs, 30 days of Curcumin C3 Complex cut serum MMP-3 by 24.5% and TNF-α by 20.8% alongside better comfort scores (Zheng 2025).Canine trial
  • In 20 client-owned dogs, curcumin with boswellia produced significant gains in force-plate measures of movement (Caterino 2021).Canine RCT
  • Dietary curcumin limited intestinal mast cell expansion and supported a balanced gut immune response (Kinney 2015).Preclinical

Bromelain

50 mg

Pineapple-stem enzymes with two jobs: they are the classic absorption partner for curcumin and quercetin, and they help support a balanced inflammatory response and comfortable digestion on their own.

  • In 30 dogs, a 28-day bromelain supplement lowered faecal calprotectin and cortisol and raised short-chain fatty acids (Atuahene 2023).Canine trial
  • Bromelain was linked to fewer eosinophils and lower IL-13 in an allergen-driven model (Secor 2005).Preclinical
  • Over 16 weeks, 500 mg/day oral bromelain improved comfort and function scores plus antioxidant markers (Kasemsuk 2016).Human RCT

Black Pepper Extract

5 mg · 95% piperine

The doorman of the formula. Piperine slows the rapid breakdown of plant compounds in the gut wall and liver, so more of what your dog swallows actually reaches the bloodstream instead of passing straight through.

  • In Beagles, adding piperine raised plasma levels of active plant compounds roughly 1.5–3 fold (Boonyarattanasoonthorn 2022).Canine PK
  • Piperine markedly increased how much curcumin actually reaches the bloodstream (Shoba 1998).Human PK
  • Piperine supported a calmer Th2-type response and less ear swelling in an allergic-skin model (Choi 2020).Preclinical

Zinc (Chelated)

15 mg

The cofactor behind the enzymes that build keratin and knit the skin barrier together. We use an amino-acid-bound form, because that bond helps protect zinc on its way through the gut and supports better uptake.

  • In northern-breed dogs with zinc-responsive skin changes, supplemental zinc was followed by complete resolution of lesions in 15 of 17 dogs (Colombini 1997).Canine series
  • Senior dogs on chelated zinc grew longer, faster-growing hair with smoother cuticles and less shedding than on inorganic minerals (Amundson 2025).Canine RCT
  • Dogs on chelated zinc showed a more favourable faecal microbiota profile than dogs on inorganic zinc (Pereira 2021).Canine crossover

Multi-Strain Probiotics

2 Billion CFU

Itchy skin often starts further down. Around 70% of immune tissue sits along the gut, where bacteria help train immune cells to tell friend from foe. A diverse microbiome supports measured responses to everyday triggers — and firmer stools.

  • Puppies from atopic parents given L. rhamnosus GG early showed lower allergen-specific IgE and milder skin-test reactions (Marsella 2009).Canine trial
  • In 41 dogs across 19 clinics, 12 weeks of L. paracasei K71 supported comfortable skin with a greater drop in medication scores than controls (Ohshima-Terada 2015).Canine RCT
  • Atopic dogs had lower gut microbial diversity than healthy dogs; 16 weeks of probiotics improved skin-lesion and itch scores (Song 2025).Canine study

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. Studies cited refer to individual ingredients, not the finished product.

Now in chew form.

Built from the list above

BestsellerAllergy & Itch Soft Chews
Vet
Formulated
VET FORMULATED ALLERGY CHEWS

Allergy & Itch Soft Chews

8.82oz / 250g / 100 chews

4.8 — based on 157 verified reviews
  • Reduces Itching & Scratching
  • Supports Healthy Skin & Coat
  • Immune System Support
  • Delicious Taste Dogs Love
ChickenBeefCorn, wheat & soyArtificial flavours
From $54.95≈ 1 month of daily support
SHOP ALLERGY & ITCH

30-Day Make-It-Right Guarantee